Identification of a chemotactic sensitivity in a coupled system.
نویسندگان
چکیده
Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation and vascular tumours provide a focus on optimization strategies. Experiments can characterize the form of possible chemotactic sensitivities. This paper addresses the recovery of the chemotactic sensitivity from these experiments while allowing for non-linear dependence of the parameter on the state variables. The existence of solutions to the forward problem is analysed. The identification of a chemotactic parameter is determined by inverse problem techniques. Tikhonov regularization is investigated and appropriate convergence results are obtained. Numerical results of concentration-dependent chemotactic terms are explored.
منابع مشابه
A Parametric Study for Identification of the Variables in Tidally Affected Pond Systems (TECHNICAL NOTE)
In this paper a parametric study was undertaken to quantify the sensitivity Abstract to a wide range of coastal detention pond systems dealing with tidal influence to store surface flood water so as to produce general guidance on the importance of the catchment and pond variables. In this process a specified pond design return period was selected for which the system was to be designed. The pon...
متن کاملSurvival and Chemotactic Behavior of H pylori at Different Media pH
Background: H pylori is a human gastric pathogen. Chemotaxis is an essential factor in colonization of H pylori, but very little is known about its chemotactic responses at different pH conditions, especially in acidic environment of stomach as its natural habitant. Methods: We first determined survival of H pylori under various pH conditions in the presence and absence of urea. Chemotaxis was...
متن کاملDynamic Response of the Coupled Vehicle-Floating Slab Track System using Finite Element Method
In present study, a mathematical model of the vehicle–floating slab track (FST) interaction is established to investigate the coupled behaviour of vehicle–track system. The FST is modelled as the double Euler -Bernoulli beam including the rail and slab. The railway vehicle is simplified as a multi-rigid-body model. The wheel–rail interface is treated using a nonlinear Hertzian contact model, co...
متن کاملI-8: Sperm Chemotaxis towards Progesterone,A Guiding Mechanism That May Be Used to Select The Best Spermatozoa for Assisted Reproduction
Background: Spermatozoa are able to sense an attractant molecule gradient and as a consequence, orient their movement towards the source of the attractant. This mechanism is known as sperm chemotaxis. In recent years, our laboratory contributed to the knowledge of several features of mammalian sperm chemotaxis. These include the size and physiological state of the chemotactic sperm population, ...
متن کاملDEFECTIVE NEUTROPHIL MOBILITY IN TEN PATIENTS WITH VITAMIN D-DEFICIENT RICKETS
We studied the immune system, especially the chemotactic activity of neutrophils, in ten patients with vitamin D-deficient rickets and compared the results with ten healthy controls of matched age. Among all immune system factors, the chemotactic studies persistantly showed remarkable deficiency in leukocyte mobility, both random motion and migration. When compared with controls, the findi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Mathematical medicine and biology : a journal of the IMA
دوره 25 3 شماره
صفحات -
تاریخ انتشار 2008